We suggest suppressing the first sentence from section 3

We surmise that results obtained from the experiments described in this section cannot serve to understand the role of I_NaL in arrhythmogenesis.

step 1. Van Driessche W, Lindemann B: Quantity reliance out of currents courtesy solitary salt-choosy pores into the frog skin. Characteristics. 1979; 282 (5738): 519-520 PubMed Abstract | Blogger Full Text message

This means the fresh strong conclusions put forward from this manuscript is actually not justified and that i do not agree brand new manuscript within this function

The latest people possess clarified a number of the issues I increased into the my personal earlier feedback. Unfortunately, most of the big dilemmas haven’t been addressed by this modify. Once i manufactured in my previous opinion, We deem it impractical that most people points will be set simply from the a few additional sentences. Rather you can still find specific basic concerns into the fresh construction and you may, extremely significantly, with the data.

It indicates the newest good findings put forward from this manuscript try perhaps not justified and i also don’t approve brand new manuscript inside means

The latest writers has made clear a number of the issues I raised inside my earlier feedback. Unfortuitously, the biggest troubles have not been treated through this revise. Whenever i produced in my personal prior remark, We deem they impractical that men and women factors are repaired simply from the a number of added paragraphs. Instead you can still find specific basic issues to the fresh framework and you can, really significantly, to the data.

• The best issue is that if We used this new description from the ways in the last type it actually was it is possible to in order to decode, that have nearly best accuracy, people haphazard stimulus labels We picked. Select getting examples of so it reanalysis. Whether or not i pretend that the actual stimulus searched from the an afterwards day or was continuously alternating ranging from rule and silence, the brand new decoding is obviously alongside best. This might be an indication the decoding has nothing to accomplish for the actual stimuli heard because of the Transmitter but is opportunistically exploiting various other possess regarding the analysis. The fresh handle analysis the fresh new authors did, reversing the fresh new stimulus names, don’t target this dilemma whilst suffers from alike situation. Basically, just what classifier is presumably using is the time who’s passed as recording been.
• The reason for it is allegedly that the article authors made use of non-separate data for studies and you will review. Of course I understand accurately (select point 3), arbitrary sampling 1 / 2 of information examples out of a keen EEG trace are not separate research. Repeated the research five times the newest manage study the new writers performed isnt an acceptable means to fix target it concern. At random looking trials of a period of time collection that contains sluggish change (for instance the slow trend craft you to presumably reigns over this type of tracks significantly less than these circumstances) often invariably include good temporal correlations. Find TemporalCorrelations.jpg set for 2D occurrence histograms and you will a relationship matrix exhibiting that it.
• Due to the fact changed methods section will bring increased detail today, it still is unclear about what study were utilized. Traditional category research statement just what data features (common articles on the investigation matrix) and you will what observations (typical rows) were utilized. Things could be a component but usually that is brand new additional EEG channels or fMRI voxels etc. Observations are often time affairs. Right here I suppose new experts transformed new intense products into good more place using prominent parts research. This is simply not said in the event the dimensionality was less making use of the eigenvalues. In any event, I suppose the knowledge samples (built-up within 128 Hz) was after that utilized as observations plus the EEG channels transformed from the PCA were https://www.essayrevisor.com/research-paper-writing-service/ utilized once the provides. The newest stimulus labels were tasked since the On the or Off for every shot. A collection of 50% regarding trials (and you can labels) was then chose randomly having studies, as well as the rest was utilized to have investigations. So is this correct?